（旧版）「喘息ガイドライン作成に関する研究」平成11年度研究報告書/ガイドライン引用文献(2000年まで)簡易版抄録を掲載

6.文献

発作入院,喘息死亡防止に関する論文:

1. Donahue JG, Weiss ST, Livington JM, et al. Inhaled steroids and the risk of hospitalization for asthma. JAMA 1997; 277: 887-891. (IV A)
2. Suissa S, Ernst P, Benayoun S, et al. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Eng J Med 2000; 343; 332-336. (IV A)

吸入ステロイド薬の軽症例および早期導入に関する論文:

3. Malo JL, Cartier A, cote J, et al. Influence of inhaled steroids on recovery from occupational asthma after cessation of exposures: an 18-month double blind cross-over study. Am J Respir Crit Care Med 1996; 153: 953-960. (II A)
4. Overbeek SE, Kerstjen HAM, Bogaard JM, et al. Is delayed introduction of inhaled corticosteroids harmful in patients with obstructive airways disease (athma and COPD)? Chest 1996; 110: 35-41. (II A)
5. Osterman K, Carlholm M, Ekelund J, et al. Effect of 1-year daily treatment with 400 budesonide in newly diagnosed asthma. Eur Resp J 1997; 10: 2210-2215. (II A)
6. Jatakanon A, Kharitonof S, Barnes PJ. Effect of differing dose of inhaled budesonide on markers of airway inflammation in patients with mild asthma. Thorax 1999; 54: 108-111. (II A)
7. The childhood asthma management program research group. Long-term effects of budesonide or nedcromil in children with asthma. N Eng J Med 2000; 343: 1054-1063. (II A)
8. van der Grunsven OM, van Schayck CP, Molema J, et al. Effect of inhaled corticosteroids on bronchial responsiveness in patients with corticosteroid naive mild asthma. Thorax 1999; 54: 316-322. (I A)
9. Convery RP, Leitch DN, Bromly C, et al. Effect of inhaled fluticasone propionate on airway responsiveness in yreaatment-naive individuals-a lesser benefir in female. Eur Respir J 2000; 15: 19-24. (II A)
10. Verberne AAPH, Frost C, Roorda RJ, et al. One year treatment with salmeterol compared with beclomethasone in children with asthma. Am J Respir Crit Care Med 1997; 156: 688-695. (II A)
11. Reed CE, Offord KP, Nelson HS, et al. Aerozol beclomethasone dipropionate spray compared with theophyllin as primary treatment for chronic mild to mederate asthma. J Allergy Clin Immunol 1998; 101: 14-23. (II A)
12. Malmstrom K, Rodrigez-Gomez G, Guerra J, et al. Oral montelukast, inhaled beclomethasone, and プラセボ for chronic asthma. A randomized, controlled trial. Ann Intern Med 1999; 130: 487-495. (II A)
13. Bleecker ER, Welch MJ, Weinstein SF, et al. Low-dose inhaled fluticasone propionate versus oral zafiriuakst in the treatment of persistent asthma. J Allergy Clin Immunol 2000; 105: 1123-1129. (II A)
14. Olivieri D, Chetta A, Donno ML, et al. Effect of short term treatment with low-dose inhaled Fluticasone propionate on airway inflammation and remodeling in mild asthma; a プラセボ controlled study. Am J Respir Crit Care Med 1997; 155: 1864-1871(II A)

吸入ステロイド薬と併用薬:

15. Woolcock AJ, Lundback B, Ringdal N, et al. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am J Respir Crit Care Med 1996; 153: 1481-1488(II A)
16. Pauwels RA, Lofdahl C, Postma DS, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N Engl J Med 1997; 337: 1405-1411(II A)
17. Ukena D, Harnest U, sakalauskas R, et al. Comparison of addition of theophylline to inhaled steroid with doubling of the dose of inahaled steroid in asthma. Eur Respir J 1997; 10: 2754-2760(II A)
18. Evans DJ, Taylor DA, Zetterstrom O, et al. A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma. N Engl J Med 1997; 337: 1412-1418(II A)
19. Crompton GK, Ayres JG, Basran G, et al. Comparison of oral bambuterol and inhaled salmeterol in patients with symptomatic asthma and using inhaled corticosteroids. Am J Respir Crit Care Med 1999; 159: 824-828(II A)
20. van Noord JA, Schreurs AJM, Mol SJM, et al. Addition of salmeterol versus doubling the dose of fluticasone propionate in patients with mild to moderate asthma. Thorax 1999; 54: 207-212(II A)
21. Laviolette M, Malmstrom K, Lu S, et al. Monterukast added to inhaled beclomethasone in treatment of asthma. Am J Respir Crit Care Med 1999; 160: 1862-1868(II A)
22. Christian Virchow Jr J, Prasse A, Naya I, et al. Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids. Am J Respir Crit Care Med 2000; 162: 578-585(II A)
23. Kips JC, O'Connor BJ, Inman MD, et al. A long term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma. Am J Respir Crit Care Med 2000; 161: 996-1001(II A)
24. Shrewsbury S, Pyke S, Britton M. Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA). BMJ 2000; 320: 1368-1373(I A)
25. Tamaoki J, Kondo M, Sakai N, et al. Leukotrien antagonist prevents exaverbation of asthma during reduction of high-dose inhaled corticosteroid. Am J Respir Crit Care Med 1997; 155: 1235-1240(II A)
26. Lofdahl CG, Reiss TF, Leff JA, et al. Randomised, プラセボ controlled trial of effect of a leukotriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatic patients. BMJ 1999; 319: 87-90(II A)
27. Tamaoki J, Kondo M, Sakai N, et al. Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Lancet 2000; 356: 273-278(II A)
28. Shapiro G, Lumry W, Wolfe J, et al. Combined salmeterol 50mcg and fluticasone propionate 250mcg in the diskus device for the treatment of asthma. Am J Respir Crit Care Med 2000; 161: 527-534(II A)
29. Kavuru M, Melamed J, Gross G, et al. Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: A randomised, double blind, プラセボ controlled trial. J Allergy Clin Immunol 2000; 105: 1108-1116(II A)

吸入ステロイド薬の全身的影響:

30. Lipworth BJ. Systemic Adverse Effects of Inhaled Corticosterold Therapy. A Systematic Review and Meta-analysis. Arch Intern Med 1999; 159: 941-955(I)
31. Aaronson D, Kaiser H, Dockhorn H, et al. Effects of budesonide by means of the Turbuhaler on the hypothalmic-pituitary-adrenal axis in asthmatic subjects: A dose-response study. J Allergy Clin Immunol 1998; 101: 312-319(II)
32. Lipworth BJ, Clark DL, McFarlane LC. Adrenocoritical activity with repeated twice daily dosing of fluticasone propionate and budesonide given via a large volume spacer to asthmatic school children. Thorax 1997; 52: 686-689(II)
33. Li JTC, Goldstein MF, Gross GN, et al. Effects of fluticasone propionate, triamcinolone acetonide, prednisone, and プラセボ on the hypothalamic-pituitary-adrenal axis. J Allergy Clin Immunol 1999; 103: 622-628(II)
34. Ayres JG, Bateman ED, Lundback B, et al. High dose fluticasone propionate, 1mg daily, versus fluticasone propionate 2mg daily, or budesonide, 1.6mg daily, inpaticents with chronic severe asthma. Eur Respir J 1995; 8: 579-586(II)
35. Hughes JA, Conry BG, Male SM, et al. One year prospective open study of the effect of high dose inhaled steroids, fluticasone propionate, and budesonide on bone markers and bone mineral density. Thorax 1999; 54: 223-229(II)
36. Pauwels RA, Yernault JC, Demedts MG, et al. Safety and Efficacy of Fluticasone and Beclomethasone in Moderate to Severe Asthma. Am J Respir Crit Care Med 1998; 157: 827-832(II)
37. Medici TC, Grebski E, Hacki M, et al. Effect of one year treatment with inhaled fluticasone propionate or beclomethasone dipropionate on bone density and bone metabolism: a randomised parallel group study in adult asthmatic subjects. Thorax 2000; 55: 375-382(II)
38. Egan JJ, Maden C, Kalra S, et al. A randomized, double-blind study comparing the effects of beclomethasone and fluticasone on bone density over two years. Eur Respir J 1999; 13: 1267-1275(II)

採用しなかった論文:

39. Goldman M, Rachmiel M, Gendler L, et al. Decrease in asthma mortality rate in Israel from 1991-1995: Is it related to increased use of inhaled corticosteroids? J Allergy Clin Immunol 2000; 105: 71-74(IV B)
40. van der Molen T, Jong BM, Mulder HH, et al. Starting with higher dose of inhaled corticosteroids in primary care asthma treatment. Am J Respir Crit Care Med 1998;148: 121-125(II B)
41. Jatakanon A, Lim S, Barnes PJ. An inhaled steroid improve markers of airway inflammtion in patients with mild asthma. Eur Respir J 1998; 12: 1084-1088(II B)
42. Jonasson G, Calsen K-H, Blomqvist P. Clinical efficacy of low-dose inhaled budesonide once or twice daily in children with mild asthma not previously treated steroids. Eur Respir J 1998; 12: 1099-1104(II B)
43. Fahy JV, Boushey HA. Effect of low-dose beclomethasone dipropionate on asthma control and airway inflammation. Eur Respir J 1998; 11: 1240-1247(II B)
44. Tamaoki J, Nakata J, Nishimura K, et al. Effect of inhaled indomethacin in asthmatic patients taking high doses of inhaled corticosteroids. J Allergy Clin Immunol 2000; 105: 1134-9(II C)
45. Rivington RN, Boulet LP, Cote J, et al. Esfficacy of Uniphyl, salbutamol, and their combination in asthmatic patients on high-dose inhaled steroids. Am J Respir Crit Care Med 1995; 151: 325-332(II B)
46. Bootsma GB, Dekhuijzen PNR, Festen F, et al. Fluticasone Propionate Does not Influence Bone Metabolism in Contrast to Beclemethasone Dipropionate. Am J Respir Crit Care Med 1996; 153: 924-930(II)