Minds Tokyo GRADE Center
(Updated March 12, 2020)
This section introduces information related to Minds Tokyo GRADE Center, GRADE working group, and GRADE approach.
Minds Tokyo GRADE Center

Minds Tokyo GRADE Center is an organization established to disseminate the GRADE approach in Japan. It was established by the Japan Council for Quality Health Care in March 2019. The main activities are as follows:.
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The video about Minds Tokyo GRADE Center Commemorative Event
The following events were held on November 29-30. Please refer to the following for details such as lecture videos.
・Minds Tokyo GRADE Center Commemorative Speeches
・The 22nd Japanese Clinical Practice Guideline Development Groups Conference
・The 1st Minds Tokyo GRADE Center Workshop
GRADE working group

The GRADE working group is an international working group of individuals who develop and provide the GRADE approach. Here we have gathered various information on the GRADE approach. |
GRADE Handbook
The GRADE Handbook introduces the process for using the GRADE approach.
GRADE Series in Journal of Clinical Epidemiology
In the Journal of Clinical Epidemiology, we introduce the GRADE approach by topic. Currently, there are the following articles.
- GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
- GRADE guidelines: 2. Framing the question and deciding on important outcomes
- GRADE guidelines: 3. Rating the quality of evidence
- GRADE guidelines: 4. Rating the quality of evidence-study limitations (risk of bias)
- GRADE guidelines: 5. Rating the quality of evidence-publication bias
- GRADE guidelines 6. Rating the quality of evidence-imprecision
- GRADE guidelines: 7. Rating the quality of evidence-inconsistency
- GRADE guidelines: 8. Rating the quality of evidence-indirectness
- GRADE guidelines: 9. Rating up the quality of evidence
- GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence
- GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes
- GRADE guidelines: 12. Preparing Summary of Findings tables-binary outcomes
- GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles-continuous outcomes
- GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations
- GRADE guidelines: 15. Going from evidence to recommendation-determinants of a recommendation's direction and strength
- GRADE Guidelines: 16. GRADE evidence to decision frameworks for tests in clinical practice and public health
- GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence
- GRADE guidelines: 18. How ROBINS-I and other tools to assess risk of bias in nonrandomized studies should be used to rate the certainty of a body of evidence
- GRADE Guidelines: 19. Assessing the certainty of evidence in the importance of outcomes or values and preferences—Risk of bias and indirectness
- GRADE guidelines: 20. Assessing the certainty of evidence in the importance of outcomes or values and preferences—inconsistency, imprecision, and other domains
- GRADE guidelines: 21 part 1. Study design, risk of bias and indirectness in rating the certainty across a body of evidence for test accuracy
- GRADE guidelines: 21 part 2. Inconsistency, Imprecision, publication bias and other domains for rating the certainty of evidence for test accuracy and presenting it in evidence profiles and summary of findings tables.
- GRADE guidelines: 22. The GRADE approach for tests and strategies—from test accuracy to patient-important outcomes and recommendations
- GRADE guidelines 26: informative statements to communicate the findings of systematic reviews of interventions.
- GRADE guidelines 27: how to calculate absolute effects for time-to-event outcomes in summary of findings tables and Evidence Profiles.
- GRADE Guidelines 28: Use of GRADE for the assessment of evidence about prognostic factors: rating certainty in identification of groups of patients with different absolute risks
Evidence to Decision (EtD) Frameworks
- GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction
- GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines