ガイドライン

(旧版)科学的根拠に基づく
膵癌診療ガイドライン 2006年版

書誌情報
 
CQ2 化学療法


CQ2-1 局所進行切除不能膵癌に対し,化学療法単独による治療は推奨されるか?

【引用文献】
1) Klaasen DJ, Maclntyre JM, Catton GE, Engstrom PF, Moertel CG. Treatment of locally unresectable cancer of the stomach and pancreas: A randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil - an Eastern Cooperative Oncology Group Study. J Clin Oncol 1985; 3: 373-378.
2) Fung MC,高山史真子,石黒 洋,坂田 徹,安達 進,森實敏夫.進行性・転移性膵癌に対する化学療法-30年間にわたる43ランダム化比較臨床試験の分析(1974-2002年)-.癌と化学療法 2003; 30: 1101-1111.
3) Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD. Improvements in survival and clinical benefit with Gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 1997; 15: 2403-2413.
4) Rocha Lima CM, Green MR, Rotche R, Miller WH Jr, Jeffrey GM, Cisar LA, Morganti A, Orlando N, Gruia G, Miller LL. Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 2004; 22: 3776-3783.


 

書誌情報